PARKINSON'S DISEASE RISK FACTOR , SIGN AND SYMPTOM , DIAGNOSIS , TREATMENT ~ Medical diseases and trems ,symptoms causes TREATMENT

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PARKINSON'S DISEASE RISK FACTOR , SIGN AND SYMPTOM , DIAGNOSIS , TREATMENT

                                             PARKINSON DISEASE



         It is a degenerative disease and also progressive in nature , in this condition the level of dopamine neurotransmitter become decrease in the brain.

        * In this condition the substantia nigra of the basal ganglia become disturbed so dopamine production become decrease . In this condition the globus pallidus release excessive ACH.

  RISK FACTOR

           * Old age more then 50 year .

           * Head injury .

           * Patient receiving antipsychotic drug .

  SING AND SYMPTOM

        * Symptom appear due to two reason 

                               - decrease dopamine level

                               - Increase ACH level.[ Acetylcholine hormone ]

        * Tremors - Resting tremors occur 

                          - These tremors only appear during resting condition and the tremors does not appear during any physical activity and also during sleeping .

        * Pill rolling tremors occur. 

        * Rigidity - Cog wheel rigidity.

        * bradykinesia.

        * Micrographia 

        * Drooling of saliva

        * stooped posture 

        * Propulsive walk

        * Mask like face.

        * Monotonous speech.

 DIAGNOSIS

         Physical examination.

         CT Scan

         MRI Scan

 TREATMENT

    MEDICAL MANEGEMENT

          The drug of choice is levodopa but it should be administer with Carbidopa.

  The carbidopa is Dopamine decarboxylase enzyme inhibitor . so it prevent the metabolism of levodopa in the liver .

* The other choice is Bromocriptine and cabergoline.

 * The symptomatic treatment can be provided for tremors and seizures.

 * The anti cholinergic medication should be administered .

 NURSING MANAGEMENT 

    * Prevent injury to the patient during ambulation .

    * Advise the patient to sleep in the on the frame surface .

    * Advise to the patient to avoid vitamin B6.

     

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